Curative effects of the ethanolic extract of leaves of Solanum torvum on obese, diabetic -induced albino rats

 
 
International Journal of Biotech Trends and Technology (IJBTT)
 
© 2012 by IJBTT Journal
Volume - 2 Issue - 3                          
Year of Publication : 2012
Authors :Vasuki .R, Rajeswari Hari

Vasuki .R, Rajeswari Hari "Curative effects of the ethanolic extract of leaves of Solanum torvum on obese, diabetic -induced albino rats",International Journal of Biotech Trends and Technology (IJBTT), V2(3):9-15 July - September 2012. Published by Seventh Sense Research Group.

Abstract

The present study dealt with the investigation of anti-obesity and anti-diabetic effects of ethanolic extract of leaves of Solanum torvum (STE) using obese, diabetic -induced albino rats. The animals received either normal diet, high-fat diet or high-fat diet with additional STEfor 12 weeks. After the end of administration, body weight, plasma glucose, insulin, and liver triglyceride, Cholesterol Content and antioxidant activity were measured. The result revealed that , compared to the high-fat diet group, increases in body weight, plasma glucose and insulin were significantly suppressed for STE groups.STE also proved to possess good antioxidant activity.

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Keywords
These results suggest that STE is expected to be an useful plant extract for alleviating the adversse effect of obesity associated with diabetes mellitus.