IJBTT

Pharmacological Study of Trichodesma Indicum

	International Journal of Biotech Trends and Technology (IJBTT)
	© 2014 by IJBTT Journal
	Volume - 4 Issue - 2
	Year of Publication : 2014
	Authors :Mohana Priya. R ,  Senthilkumar. P
	10.14445/22490183/IJBTT-V5P601

Citation

"Pharmacological Study of Trichodesma Indicum",International Journal of Biotech Trends and Technology (IJBTT), V4(2):1-5 Apr - Jun 2014. Published by Seventh Sense Research Group.

Abstract

Objective: To investigate the phytochemical screening and selected pharmacological activities of the methanolic extract of the plant Trichodesma indicum. Methods: The antibacterial potential of the methanolic leaf extract of the studied species was tested against Escherichia coli,Pseudomonas aeruginosa, Klebsiella pneumonia, Streptococcus pyrogens and Bacillus subtilis by agar well diffusion method. The higher zone of inhibition (15mm) was observed against the bacterium Bacillus subtilisat (100?l) concentration of methanol leaf extract. Results: Preliminary phytochemical analysis of studied species shows that presence of phytochemical compounds like alkaloids, tannins, reducing sugars and flavonoids. GC-MS analysis confirms the occurrence of 20 different compounds in the methanol leaf extract of the both studied species. Conclusions: The obtained results provide a support for the use of this plant in traditional medicine but further pharmacokinetics studies are required.

References

1. Arumugam M, Karthikeayan S, and Ahmed John, S. Antibacterial activity of Indonessiellaechioides. Research Journal of Biological Science 2009. 1(3): 157-161.
2. Stary F and Hans S. The National guides to medical herbs and plants.Tiger Books. Int. Plc. UK 1998. 3. Del Campo J, Amiot MJ, and Nguyen C. Antimicrobial effect of Rosemary extract. J. Food Protect.2000; 63: 1359-1368.
4. Mann A, Banso A and Clifford LC. An antifungal property of crude plant extracts from Anogeissusleiocarpus and Terminaliaavicennioides. Tanzania J. Health Res 2008; 10 (1) 34-38.
5.Mothana RA and Lindequist U. Antimicrobial activity of some medicinal plants of the island Soqotra. J. of Ethnopharmacology 2005; 96: 177-181.
6. Bajpai M, Pande A, Tewari SK, and Prakash D. Phenolic contents and antioxidant activity of some food and medicinal plants. International Journal of Food Sciences and Nutrition 2005; 56(4): 287-291 .
7. Wojdylo A, Oszmianski J and Czemerys R. Antioxidant activity and phenolic compounds in 32 selected herbs. Food Chemistry 2007; 105: 940-949.
8. Babu PD, and Subhasree RS.Antimicrobial activities of Lawsoniainermis - a review.Acad J Plant Sci2009; 2(4): 231-232.
9. Reddy PS, Jamil K and Madhusudhan P. Antibacterial activity of isolates from Piper longumand Taxusbaccata. Pharma.Biol 2001; 39: 236-238.
10. Ateb DA, and Erdourul OT, Antimicrobial activities of various medicinal and commercial plant extracts. Turk. J. Biol 2003; 27:157-162.
11.Thirupathy S, Sisubalan N, Malayaman V, GhouseBashaM.Phytochemical Analysis and Antibacterial Activity of Tephrosiahookerianawight and Arn against human pathogens.Int. J. Pharm. Sci. Rev. Res2014; 24(2): 53-56.
12.Mittal PK,Subbarao SK. Prospects of using herbal products in the control of mosquito vectors.ICMR Bull 2003; 33:1-10.
13.Chessbrough M. Medical laboratory manual for Tropical countries; 2000 Linacre House, Jordan Hill, Oxford.
14. Iyengar MA. Study of drugs. 8th edition, Manipal Power Press, Manipal, Indi ;1995.
15.Vasantharaj S, Sathiyavimal S, Hemashenpagam N, Phytochemical Analysis and Antibacterial Activity of Azadirachtaindica, Int. J. Pharm. Sci. Rev. Res;2013; 22(1):59-61.
16.SrivastavaA, Shukla Kumar YN. Recent development in plant derived antimicrobial constituents A Review. J Med Arom Pl. Sci 2000; 20: 717-72.
17.SaradhajyothiKoona, SubbaraoBudida.Antimicrobial potential of the extracts of the leave of AzadirachtaindicaLinn.Nat SciBiol 2011; 3(1):65-69.
18. SenthilKumar RP, Sheeba Christina A, Malayaman V, Sathiyavimal S, Vasantharaj S, Analysis of phytochemical Constituents and Antibacterial Activity of PhyllanthusrheedeiAgainst Human Pathogens, Int. J. pharm. Sci. Rev.Res 2013; 22(1):158-160.
19.Senthilkumar RP, Malayaman Vand Sindhuja S. Phytochemical screening and antibacterial evaluation of the leaf, flower and seed coat extracts of Cassia alata L. Journal of Chem and Phar Res 2013; 5(11):740-744.
20.Senthilkumar P, SambathR, Vasantharaj S. Antimicrobial Potential and Screening of Antimicrobial compounds ofRuellia tuberose Using GC-MS.Int. J. Pharm. Sci. Rev. Res 2013; 20(1) :184-188.

Keywords
Methanol extract ofTrichodesma indicum, Phytochemical Analysis, Antibacterial activity, GC-MS analysis.