Citation :

R. SreeLatha, K. Ramya, "Structure Analysis of Wild type HIV-I Proteases," International Journal of Computer Trends and Technology (IJCTT), vol. 6, no. 2, pp. 34-36, 2016. Crossref, https://doi.org/10.14445/22490183/IJBTT-V17P604

Abstract

Understanding the reactivity of the human immunodeficiency virus (HIV–1)is an emerging area in the field of drug design. The present article high lights the structure analysis of HIV-1 protease.

Keywords

HIV–1, aspartylprotease.

References

1. Wlodawer, A., Miller, M., Jaskolski, M., Sathyanarayana, B.K., Baldwin, E., Weber, I.T., Selk, L.M., Clawson, L., Schneider, J., Kent., S.B.H. Science 1989, 245, 616-621.
2. Kramer, R. A.; Schaber, M. D.; Skalka, A. M.; Ganguly, K.; Wong-Staal, F.; Reddy, E. P. HTLV-III gag Protein Is Processed in Yeast Cells by the Virus pol-Protease. Science 1986, 231, 1580-1585`.
3. R. SreeLatha, R. Vijayaraj, E. R. AzhagiyaSingam, K. Chitra and V. Subramanian, “3D-QSAR and Docking Studies on the HEPT Derivatives of HIV-1 Reverse Transcriptase”, Chemical Biology & Drug Design 78 (2011) 418–426. (Camila S, et al., 2004)
4. PDB code Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases Biochemistry1996.
5. Alexander Wlodawer and Jiri Vondrasek (1998).INHIBITORS OF HIV-1 PROTEASE: A Major Success of Structure-Assisted Drug Design. Annu. Rev. Biophys.Biomol. Struct. 27:249-84
6. P. J. Gane and P. M. Dean, “Recent advances in structurebased rational drug design”, Current Opinion in. Structural Biology, 2000, 10, 401-404. (Marrone TJ, Briggs JM and McCammon ,1997)
7. J. A. EWING, IRWIN D. KUNTZ ... Sons, Inc. J ComputChem 18: 11751189, 1997
8. Wang J, Kollman PA and Kuntz ID Understanding the bacterial polysaccharide antigenicity of Streptococcus 104:203–209,1999
9. Carlson H.A., McCammon J.A. (2000) Accommodating Protein Flexibility inComputational Drug Design. Molecular Pharmacology 57: 213-218
10. Toraskar, Mrunmayee P.. "HIV-1 Protease Inhibitor : A Review", Journal of Pharmacy Research/09746943, 2009 Publication
11. Balakrishnan, M.. "Homology Modeling andDocking Studies Between HIV-1 Protease andBeta Mercapto Ethanol", IUP Journal ofBiotechnology/0973849520091201
12. Udayakumar, R., Kaliyamurthie, K.P., Khanaa, Thooyamani, K.P., Data mining a boon: Predictive system for university topper women in academia, World Applied Sciences Journal, v-29, i-14, pp-86-90, 2014.
13. Lingeswaran, K., Prasad Karamcheti, S.S., Gopikrishnan, M., Ramu, G., Preparation and characterization of chemical bath deposited cds thin film for solar cell, Middle - East Journal of Scientific Research, v-20, i-7, pp-812-814, 2014.
14. Premkumar, S., Ramu, G., Gunasekaran, S., Baskar, D., Solar industrial process heating associated with thermal energy storage for feed water heating, Middle - East Journal of Scientific Research, v-20, i-11, pp-1686-1688, 2014.
15. Gopalakrishnan, K., Sundeep Aanand, J., Udayakumar, R., Electrical properties of doped azopolyester, Middle - East Journal of Scientific Research, v-20, i-11, pp-1402-1412, 2014.
16. Achudhan, M., Prem Jayakumar, M., Mathematical modeling and control of an electrically-heated catalyst, International Journal of Applied Engineering Research, v-9, i-23, pp- 23013-, 2014.
17. Thooyamani, K.P., Khanaa, V., Udayakumar, R., Application of pattern recognition for farsi license plate recognition, Middle - East Journal of Scientific Research, v-18, i-12, pp- 1768-1774, 2013.