Quantitative Analysis of Lycopene Extract using Pretreated Tomato Samples

International Journal of Biotech Trends and Technology (IJBTT)
© 2016 by IJBTT Journal
Volume - 6 Issue - 1                          
Year of Publication : 2016
Authors : Sanchit Seth, Oishee Chatterjee


Sanchit Seth, Oishee Chatterjee "Quantitative Analysis of Lycopene Extract using Pretreated Tomato Samples", International Journal of Biotech Trends and Technology (IJBTT), V6(1): 18-21 Jan - Mar 2016, Published by Seventh Sense Research Group.


Tomatoes are used extensively in the kitchens worldwide. These are basically used to enhance the flavor and also used as the coloring agent. Tomatoes are rich source of carotenoids, flavonoids and various other antioxidants. The red color imparted by tomatoes is mainly because of a pigment named lycopene. It is believed that lycopene has a role in managing numerous bodily functions like cell proliferation, cell to cell communication etc. Recent studies showed that lycopene can be used as the preventive measure of prostate cancer and also holds therapeutic importance to control various cancers in early stages. This research has been focused to extract lycopene from pretreated tomatoes in different conditions. Spray drier was used to prepare tomato powder which is further used as one of the samples to extract lycopene. Results were obtained from mass spectrometry to deduceconditions best suitable for pretreatment to extract maximum lycopene from tomato samples.


1. Giovannucci, E., RESPONSE: re: tomatoes, tomato-based products, lycopene, and prostate cancer: review of the epidemiologic literature. J Natl Cancer Inst, 1999. 91(15): p. 1331A-1331.
2. Takeshima, M., et al., Anti-proliferative and apoptosisinducing activity of lycopene against three subtypes of human breast cancer cell lines. Cancer Sci, 2004. 105(3): p. 252-7.
3. Hwang, E.S. and P.E. Bowen, Can the consumption of tomatoes or lycopene reduce cancer risk? Integr Cancer Ther, 2002. 1(2): p. 121-32; discussion 132.
4. Aghel N, R.Z., Amirfarkhrian S, Isolation and Quantification of Lycopene from Tomato Cultivated in Dezfoul, Iran. Jundishapur Journal of Natural Pharmaceutical Products, 2011. 6(1): p. 9-15.
5. Giovannucci, E., A review of epidemiologic studies of tomatoes, lycopene, and prostate cancer. Exp Biol Med (Maywood), 2002. 227(10): p. 852-9.
6. Pennathur, S., et al., Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid. Free Radic Biol Med, 2010. 49(2): p. 205-13.
7. Etminan, M., B. Takkouche, and F. Caamano-Isorna, The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies. Cancer Epidemiol Biomarkers Prev, 2004. 13(3): p. 340-5.
8. Gartner, C., W. Stahl, and H. Sies, Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr, 1997. 66(1): p. 116-22.
9. Angela R. Davis, W.W.F., Penelope perkins-Veazie, A rapid spectrophotometric method for analyzing lycopene content in tomato and tomato products. Postharvbio, 2003. 28: p. 425-430.

Lycopene, Drying, Spray Drying, Tomato Paste, Concentration.